Fibrometer Range

FibroMeter is a family of blood tests used to evaluate the stage of liver fibrosis. FibroMeter tests are based on clinical data along with an analysis of biochemical markers, which presence in blood reflects the degree of fibrosis in the liver. A complete range of tests for non-invasive diagnosis of liver diseases. Each FibroMeter test has been specifically designed for the main specific etiologies, using determined sets of markers.

The FibroMeter range covers the 3 main causes of liver diseases

  • Viral hepatitis (Virus)
  • Non-Alcoholic Fatty Liver Disease (NAFLD)
  • Alcoholic Liver Disease (ALD)

Note: The scores of the FibroMeter™ range have been clinically validated and patented. Please refer to the user manual for the conditions of applicability of the tests.

 
FibroMeter Virus
 

What are the results provided
by FibroMeter VIRUS?

The FibroMeter VIRUS test (Viral Hepatitis) assesses the stage of liver fibrosis in patients with chronic viral hepatitis (B, C) with or without HIV co-infection.

 

 

What parameters are used
to calculate FibroMeter VIRUS?

The test is based on patient clinical data (age, gender) and test results ofblood markers

  • Platelets
  • Alpha-2-macroglobulin
  • ALT
  • Urea
  • Prothrombin index
  • GGT
  • AST

 

 

 

 

 

 

FibroMeter VIRUS

Assesses the stage of liver fibrosis in patients with chronic viral hepatitis (B, C) with or without HIV co-infection

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

FibroMeter NAFLD

Assesses the stage of liver fibrosis in patients with metabolic steatopathy

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

FibroMeter ALD

Assesses the stage of liver fibrosis in patients with alcoholic hepatitis

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

FMVCTE
FibroMeter VCTE

Assesses the stage of liver fibrosis in patients with chronic viral hepatitis (B, C) with or without HIV coinfection, and patients with metabolic steatosis

What are the results provided
by FibroMeter VIRUS?

Fibrosis score (FibroMeter) assesses the presence of fibrosis. The score is between 0 and 1, which represents the probability of the patient presenting a significant fibrosis (METAVIR stage F2 or higher). It is displayed with an associated classification, representing the patient's presumed METAVIR stage.

Cirrhosis score (CirrhoMeter) assesses the presence of cirrhosis. This score was developed specifically for the diagnosis of cases for severe fibrosis and cirrhosis. The score is between 0 and 1, and represents the probability of the patient suffering from cirrhosis. This score is accompanied by the patient's presumed METAVIR stage.

Note: according to the patient's presumed stage, only the most appropriate classification will be displayed on the results sheet.

Activity grade (InflaMeter) assesses the necrotico-inflammatory activity caused by the virus. The score is between 0 and 1, which indicates the probable presence of significant activity (METAVIR stage A2 or above) in conjunction with the associated METAVIR activity grade.


Expert System

Certain blood markers can be affected by causes other than liver fibrosis (such as kidney deficiency, anti-coagulant treatments, etc.) That is why FibroMeter VIRUS includes an expert system that verifies the consistency of the blood marker test results. In case of abnormal values that could alter the results, the system adjusts the final FibroMeter score.

Furthermore, the health professional can manually notify fibrometer.com website of the blood marker affected by these disturbances at the time of the test.

FibroMeter NAFLD

What is the FibroMeter NAFLD test?

FibroMeter NAFLD (Non-Alcoholic Fatty Liver Disease)  assesses the stage of liver fibrosis in patients with metabolic steatopathy.


What parameters are used
to calculate FibroMeter NAFLD?

The test is based on patient clinical data (age, weight) and test results of 5 blood markers

  • Platelets
  • ASAT
  • ALAT
  • Ferritin
  • Glucose level

In addition, it is also possible to assess the fibrosis area in the liver by adding 2 other blood markers : hyaluronic acid and prothrombin index.


What results does FibroMeter NAFLD provide?

Fibrosis score (FibroMeter) assesses the presence of fibrosis. The score is between 0 and 1, which represents the probability of the patient presenting a significant fibrosis (stage F2 or higher). It is displayed with an associated classification, representing the patient's presumed METAVIR stage.

Fibrosis area (QuantiMeter) assesses the extent of liver fibrosis, expressed in percentage. This result is available only if the two additional markers (hyaluronic acid and prothrombin index) have been determined.

FibroMeter ALD

What is the FibroMeter ALD test?

FibroMeter ALD (Alcohol-related liver disease) assesses the stage of liver fibrosis in patients with alcoholic hepatitis.


What parameters are used
to calculate FibroMeter ALD?

The test is based on blood test results
of 4 biological markers

  • Alpha-2-macroglobulin
  • Hyaluronic acid
  • Prothrombin index
  • Platelets

What results does
FibroMeter ALD provide?

Fibrosis score (FibroMeter) assesses the presence of fibrosis. The score is between 0 and 1, which represents the probability of the patient presenting a significant fibrosis (METAVIR stage F2 or higher). It is displayed in conjunction with an associated classification, representing the patient's presumed METAVIR stage.

Fibrosis area (QuantiMeter) assesses the extent of liver fibrosis, expressed in percentage.

FibroMeter VCTE

What is the FibroMeter VCTE test?

FibroMeter VCTE assesses the stage of liver fibrosis in patients with chronic viral hepatitis (B, C) with or without HIV coinfection, and patients with metabolic steatosis.


What are the specific features
of FibroMeter VCTE?

FibroMeter VCTE combines the biological approach of blood scores with the physical approach provided by the ultrasonic VCTE technology of FibroScan® allowing liver stiffness measurement, to give a more accurate score, enhancing the diagnostic performance*.


What parameters are used
to calculate FibroMeter VCTE?

FibroMeter VCTE combines the FibroScan® liver stiffness measurement with the patient's clinical data (age, gender) with the results of 5 blood parameters

  • Platelets
  • Prothrombin ratio
  • ASAT
  • Alpha-2-macroglobulin
  • Gamma-GT
  • Liver stiffness

What results does FibroMeter VCTE provide?

Fibrosis score (FibroMeter) assesses the presence of fibrosis. The score is between 0 and 1, which represents the probability of the patient presenting a significant fibrosis (METAVIR stage F2 or higher). It is displayed with an associated classification, representing the patient's presumed METAVIR stage.

*Boursier et al. A new combination of blood test and FibroScan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C. Am. J. Gastro. 2011.106(7):1255-63. * Cales et al. Liver Int 2014